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Sexual Misconduct Hierarchy

on December 11, 2021

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As defined by Title IX and the CDC (2019)

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Blinded By Oxygen: Professor Sharpless's Tale

Professor Karl Barry Sharpless was the recipient of the 2001 Nobel Prize in chemistry for his work on stereoselective oxidations. Sharpless worked on the enantioselective oxidation of allylic alcohols using a titanium isopropoxide catalyst, chiral tartrate ligands, and tert -butyl hydroperoxide. He also developed an asymmetric dihydroxylation of alkenes using osmium tetroxide (OsO 4 ) and dihydroquinine based chiral ligands. In an MIT newsletter, Sharpless recounted the circumstances of his laboratory injury in 1970, not long after starting his independent career as an assistant professor at MIT, which caused him to lose sight in one eye. Late one night, Sharpless stopped to check on a graduate student before leaving the lab. The first-year was flame sealing an NMR tube in a liquid nitrogen bath. Sharpless held the tube up to the light and saw a large volume of liquid in the tube. The liquid, later realized to be liquid oxygen, quickly disappeared and the tube instantly...

Ensuring Pathways to Innovative Cures (EPIC) Act: An Amendment to the IRA to Eliminate the "Pill Penalty" Effecting the Development of New Small Molecule Drugs

SIMPLIFIED SUMMARY The Inflation Reduction Act (IRA) of 2022 includes a provision with no scientific rationale or benefit to patients that gives biologic therapeutics four years longer patent life to recoup development costs and profit than small molecule drugs. This “pill-penalty” is driving pharmaceutical companies and venture capitalists to divest away from new small molecule therapeutics. Small molecules make up almost all of oral pill medications as well as comprise most treatments for brain diseases (ex: chronic pain, migraines, schizophrenia, stroke, ALS, Parkinson’s disease, Alzheimer’s disease, MS, epilepsy, and brain caners.) Small molecules are cheaper to manufacture, store, and distribute to patients than biologics making them more accessible and economically sustainable. The Ensuring Pathways to Innovative Cures (EPIC) Act was introduced by Congressman Greg Murphy, M.D. to give small molecules and biologics the same patent life to eliminate this small molecule pen...

The Many Substances Used for At-Home Abortions Throughout History

Historically, women have been performing abortions at home for centuries, often using methods that were crude, dangerous, and ineffective. The lack of access to safe and effective medical care put women's lives at risk. Prior to the legalization of abortion in many countries, women who sought to terminate a pregnancy had limited options and faced significant health risks. Unfortunately, in desperation many women used crude physical methods to end their pregnancies included the use of tools, such as coat hangers, knitting needles, or other sharp objects, to puncture the uterus and cause bleeding. These methods were dangerous and could result in severe complications, such as infection, hemorrhage, or death. Home remedies were often the only alternative method available for women in desperate situations. Some of the most commonly used methods of home abortion included the use of toxic herbs. Women would consume these substances orally or as a vaginal suppository, hoping that they wou...

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Sexual Misconduct Hierarchy

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